The Brigham And Women’S Hospital, Inc Patent Portfolio Statistics

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The Brigham And Women’S Hospital, Inc.

Profile Summary

This article summarizes the perfomance of the assignee in the recent years. The overall statistics for this portfolio help to analyze the areas where the assignee is performing well. The filing trend, perfomance across the tech centers and the perfomance of the recent applications has been mentioned below. All the stats are calculated based on the perfomance in USPTO.

How does the overall patent portfolio of The Brigham And Women’S Hospital, Inc. look like?

Assignee Art Units
Total Applications: 1,129 1,793,438
Granted Patents: 528 941,858
Grant Index 65.27% ↓ 67.71%
Abandoned/Rejected Applications: 281 (34.73%) 449,240 (32.29%)
In-Process Applications: 313 402,340
Average Grant Time: 3.11 Years ↑ 2.91 Years
Average Office Actions: 1.99 ↑ 1.76

Which Technology Area The Brigham And Women’S Hospital, Inc. is filing most patents in? (Last 10 years)

Art Unit Definition Total Applications
Opap Parked GAU 84
1644 Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology 60
1633 Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry 38
1646 Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology 38
1647 Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology 38

How many patents are The Brigham And Women’S Hospital, Inc. filing every year?

Year Total Applications Predicted
2022 0* 462
2021 68* 367
2020 71 331
2019 100 100
2018 105 –
2017 61 –
2016 81 –
2015 85 –
2014 70 –
2013 74 –

*The drop in the number of applications filed in last two years compared to previous years is because applications can take up to 18 months to get published

Recently filed patent applications of The Brigham And Women’S Hospital, Inc. in USPTO?

Publication number: US20220233695A1
Application number: 17/616,552

Abstract:
An ultrasound system for use in unbinding an active agent from a plasma protein in a target site in a subject includes a transducer configured to generate acoustic pressure waves and a controller coupled to the transducer. The controller is programmed to control the transducer to produce a plurality of pulsed acoustic pressure waves in the target site of the patient. The plurality of pulsed acoustic pressure waves disrupt a plasma protein binding between the active agent and the plasma protein within the target site. The disruption of the plasma protein binding causes an increase in an amount of unbound active agent in the target site.

Publication date: –
Applicant: The Brigham And Women’S Hospital, Inc.
Inventors: Alexander Rotenberg

Publication number: US20220089650A1
Application number: 17/457,337

Abstract:
Sequences that enhance permeation of agents into cells and/or across the blood brain barrier, compositions comprising the sequences, and methods of use thereof.

Publication date: 2022-03-24
Applicant: The Brigham And Women’S Hospital, Inc.
Inventors: Bei Fengfeng

Publication number: US20220049221A1
Application number: 17/452,511

Abstract:
Described in the present application are methods for preparing populations of hematopoietic stem cells (HSCs), e.g., autologous and/or allogenic HSCs, using mechanical stretching or Trpv4 agonisists, and methods of use of the HSCs in transplantation. In some embodiments, the methods include providing a population comprising hemogenic endothelial (HE) cells, and (i) contacting the HE cells with an amount of an agonist of transient receptor potential cation channel-subfamily vanilloid member 4 (Trpv4); and/or (ii) subjecting the cells to cyclic 2-dimensional stretching, for a time and under conditions sufficient to stimulating endothelial-to-HSC transition. Also provided herein are methods for treating subjects who have, bone marrow, metabolic, and immune diseases; the methods include administering to the subject a therapeutically effective amount of hematopoietic stem cells (HSCs) obtained by a method described herein.

Publication date: 2022-02-17
Applicant: The Brigham And Women’S Hospital, Inc.
Inventors: Daley George Q

How are The Brigham And Women’S Hospital, Inc.’s applications performing in USPTO?

Application Number Title Status Art Unit Examiner
17/616,552 System And Method For Unbinding Of Plasma Protein-Bound Active Agents Using An Ultrasound System Docketed New Case – Ready for Examination OPAP Central, Docket
17/457,337 Methods And Compositions For Delivery Of Agents Across The Blood-Brain Barrier Non Final Action Mailed 1648 Li, Bao Q
17/452,511 Methods For Generating Functional Hematopoietic Stem Cells Docketed New Case – Ready for Examination OPAP Central, Docket
17/497,849 Self-Righting Articles – OPAP Central, Docket
17/496,578 Methods Of Identifying Drug-Modulated Polypeptide Targets For Degradation – OPAP Central, Docket